STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
resDNA restriction (DNA helicase); Cleaves DNA some 25 base-pairs downstream from the recognition site. May also act as a helicase involved in unwinding DNA at the cleavage site. Protein only required for restriction but needs the presence of the modification enzyme; Belongs to the type III restriction-modification system res protein family. (990 aa)    
Predicted Functional Partners:
mod
DNA methylase; Binds the system-specific DNA recognition site 5'-CAGAG-3'. Necessary for restriction and for methylation of A-4.
 
  
 0.981
yhdJ
Similar to E. coli putative methyltransferase (AAC76294.1); Blastp hit to AAC76294.1 (296 aa), 80% identity in aa 3 - 285; Belongs to the N(4)/N(6)-methyltransferase family.
     
 0.882
tnpA_3
Transposase for insertion sequence element is200 (SW:T200_SALTY).
      
 0.698
STM1010
Gifsy-2 prophage protein; Hypothetical protein 4 (gi|7467264).
   
  
 0.697
STM2631
Gifsy-1 prophage protein; Hypothetical protein 4 (gi|7467264).
   
  
 0.697
STM1056
Gifsy-2 prophage protein; Similar to msgA; hypothetical protein (gi|5410521).
      
 0.679
STM2741
Putative periplasmic protein.
      
 0.670
hsdR
Host restriction; similar to E. coli host restriction; endonuclease R (AAC77306.1); Blastp hit to AAC77306.1 (1188 aa), 91% identity in aa 20 - 1188.
     
 0.589
STM2636
Gifsy-1 prophage protein; Similar to integrase in phage; probable integrase (gi|7467280); Belongs to the 'phage' integrase family.
      
 0.578
STM2769
Similar to E. coli IS3 putative transposase (AAC75150.1); Blastp hit to AAC75150.1 (288 aa), 84% identity in aa 1 - 288.
      
 0.499
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.