node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alr | dadX | STM4247 | STM1802 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | 0.919 |
alr | ddlA | STM4247 | STM0380 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | D-alanine-D-alanine ligase A; Cell wall formation. | 0.947 |
alr | ddlB | STM4247 | STM0130 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | D-alanine-D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.944 |
alr | murB | STM4247 | STM4137 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation; Belongs to the MurB family. | 0.499 |
alr | murC | STM4247 | STM0129 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | L-alanine adding enzyme; Cell wall formation; Belongs to the MurCDEF family. | 0.684 |
alr | murD | STM4247 | STM0126 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.786 |
alr | murE | STM4247 | STM0123 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.807 |
alr | murF | STM4247 | STM0124 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | D-alanine:D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.970 |
alr | murG | STM4247 | STM0128 | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.488 |
dadX | alr | STM1802 | STM4247 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | 0.919 |
dadX | ddlA | STM1802 | STM0380 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | D-alanine-D-alanine ligase A; Cell wall formation. | 0.929 |
dadX | ddlB | STM1802 | STM0130 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | D-alanine-D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.938 |
dadX | ftsW | STM1802 | STM0127 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Essential cell division gene; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.420 |
dadX | murC | STM1802 | STM0129 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | L-alanine adding enzyme; Cell wall formation; Belongs to the MurCDEF family. | 0.577 |
dadX | murD | STM1802 | STM0126 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.559 |
dadX | murE | STM1802 | STM0123 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.440 |
dadX | murF | STM1802 | STM0124 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | D-alanine:D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.952 |
dadX | murG | STM1802 | STM0128 | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.440 |
ddlA | alr | STM0380 | STM4247 | D-alanine-D-alanine ligase A; Cell wall formation. | Biosynthetic alanine racemase 1; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. | 0.947 |
ddlA | dadX | STM0380 | STM1802 | D-alanine-D-alanine ligase A; Cell wall formation. | Alanine racemase 2; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | 0.929 |