Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yaiCPutative diguanylate cyclase/phosphodiesterase domain 1; Similar to E. coli orf, hypothetical protein (AAC73488.1); Blastp hit to AAC73488.1 (371 aa), 75% identity in aa 1 - 371. (370 aa)    
Predicted Functional Partners:
ylaB
Putative diguanylate cyclase/phosphodiesterase domain 2; Similar to E. coli orf, hypothetical protein (AAC73559.1); Blastp hit to AAC73559.1 (518 aa), 67% identity in aa 3 - 518.
  
 0.995
yjcC
Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC77031.1); Blastp hit to AAC77031.1 (528 aa), 64% identity in aa 1 - 528.
   
 0.993
rtn
Putative membrane protein involved in resistance to lambda and N4 phages; Similar to E. coli orf, hypothetical protein (AAC75237.1); Blastp hit to AAC75237.1 (518 aa), 70% identity in aa 1 - 518.
 
  
 0.991
STM0343
Putative diguanylate cyclase/phosphodiesterase domain 1; Similar to E. coli orf, hypothetical protein (AAC75237.1); Blastp hit to AAC75237.1 (518 aa), 31% identity in aa 10 - 512.
     0.973
STM1827
Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC74885.1); Blastp hit to AAC74885.1 (542 aa), 75% identity in aa 5 - 540.
 
  
 0.970
yhjH
Putative diguanylate cyclase/phosphodiesterase domain 3 containing protein; Similar to E. coli orf, hypothetical protein (AAC76550.1); Blastp hit to AAC76550.1 (256 aa), 79% identity in aa 2 - 256.
  
  
 0.968
yhjK
Putative diguanylate cyclase/phosphodiesterase; Similar to E. coli orf, hypothetical protein (AAC76554.1); Blastp hit to AAC76554.1 (651 aa), 84% identity in aa 1 - 651.
 
 
 0.939
yfeA
Diguanylate cyclase/phosphodiesterase domain 2; similar to E. coli orf, hypothetical protein (AAC75454.1); Blastp hit to AAC75454.1 (768 aa), 68% identity in aa 45 - 766.
  
  
 0.928
csgD
Putative transcriptional regulator; Necessary for transcription of the csgAB operon. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription (By similarity).
  
  
 0.910
yhjO
Glycosyltransferase; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix.
  
  
 0.881
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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