Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yaiAPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73492.1); Blastp hit to AAC73492.1 (63 aa), 93% identity in aa 1 - 62. (63 aa)    
Predicted Functional Partners:
gns
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74623.1); Blastp hit to AAC74623.1 (58 aa), 56% identity in aa 2 - 58; Belongs to the gns family.
   
  
 0.898
yibT
Putative cytoplasmic protein.
   
  
 0.863
ppiC
Peptidyl-prolyl cis-trans isomerase C; PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates (By similarity).
      
 0.851
STM4002
Putative cytoplasmic protein.
   
  
 0.808
aroL
Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
  
    0.745
ydhF
Putative aldo/keto reductase; Similar to E. coli orf, hypothetical protein (AAC74719.1); Blastp hit to AAC74719.1 (298 aa), 89% identity in aa 1 - 298.
   
  
 0.673
yaiI
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73490.1); Blastp hit to AAC73490.1 (192 aa), 89% identity in aa 41 - 191; Belongs to the UPF0178 family.
       0.653
yciF
Similar to E. coli putative structural proteins (AAC74340.1); Blastp hit to AAC74340.1 (166 aa), 86% identity in aa 1 - 166.
   
  
 0.581
yqjE
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76134.1); Blastp hit to AAC76134.1 (134 aa), 89% identity in aa 1 - 130.
   
  
 0.564
yhhA
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC76473.1); Blastp hit to AAC76473.1 (146 aa), 66% identity in aa 1 - 146.
   
  
 0.550
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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