Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aroMSimilar to E. coli protein of aro operon, regulated by aroR (AAC73493.1); Blastp hit to AAC73493.1 (225 aa), 77% identity in aa 1 - 225. (225 aa)    
Predicted Functional Partners:
yaiE
Putative cytoplasmic protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
 
    0.857
aroL
Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
 
  
 0.782
yiaH
Putative inner membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
    0.747
ypfG
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75519.1); Blastp hit to AAC75519.1 (347 aa), 77% identity in aa 1 - 347.
  
     0.727
mdoC
Membrane protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
  
    0.705
ybaE
Putative ABC transporter periplasmic binding protein; Similar to E. coli orf, hypothetical protein (AAC73548.1); Blastp hit to AAC73548.1 (566 aa), 79% identity in aa 1 - 565.
  
     0.673
ytfP
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77179.1); Blastp hit to AAC77179.1 (113 aa), 92% identity in aa 1 - 113.
      
 0.650
csiE
Stationary phase inducible protein; Similar to E. coli orf, hypothetical protein (AAC75588.1); Blastp hit to AAC75588.1 (433 aa), 71% identity in aa 8 - 432.
  
     0.634
damX
Membrane protein; Non-essential cell division protein.
  
     0.626
sseB-2
Similar to E. coli enhanced serine sensitivity (AAC75575.1); Blastp hit to AAC75575.1 (261 aa), 90% identity in aa 1 - 261.
  
    0.624
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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