STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proYPutative APC family, proline transporter; Permease that is involved in the transport across the cytoplasmic membrane of proline; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (456 aa)    
Predicted Functional Partners:
brnQ
LIVCS family, branched chain amino acid transporter system II (LIV-II); Component of the LIV-II transport system for branched-chain amino acids. This LIV-II transport system may be H(+)-coupled.
 
  
 0.806
yeaS
Putative transport protein; Exporter of leucine; Belongs to the Rht family.
      
 0.679
putP
SSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.663
malZ
Similar to E. coli maltodextrin glucosidase (AAC73506.1); Blastp hit to AAC73506.1 (605 aa), 83% identity in aa 2 - 605; Belongs to the glycosyl hydrolase 13 family.
     
 0.513
yciB
Putative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
      
 0.505
yggA
Putative LYSE family amino acid transport protein; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine (By similarity); Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
   
  
 0.459
pepQ
Proline dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position.
      
 0.457
gltS
GltS family glutamate transport protein; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
   
  
 0.450
proW
Glycine/betaine/proline transport protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
   
  
 0.407
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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