Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yajDPutative cytoplasmic protein; Hypothetical 12.6 Kda protein in secF-tsx intergenic region. (SW:YAJD_SALTY); Belongs to the HNH nuclease family. (115 aa)    
Predicted Functional Partners:
ychN
Putative ACR protein; Involved in intracellular sulfur reduction; similar to E. coli orf, hypothetical protein (AAC74303.1); Blastp hit to AAC74303.1 (117 aa), 92% identity in aa 1 - 117.
      
 0.896
dcoC
Oxalacetate decarboxylase: gamma chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
      
 0.858
STM3605
Putative phage endolysin.
     
 0.852
ybeB
Putative ACR, homolog of plant Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
  
 0.847
wraB
Similar to E. coli trp repressor binding protein; affects association of trp repressor and operator (AAC74089.1); Blastp hit to AAC74089.1 (198 aa), 94% identity in aa 1 - 198.
      
 0.810
ygaU
Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC75712.1); Blastp hit to AAC75712.1 (149 aa), 93% identity in aa 1 - 149.
  
  
 0.738
yfcE
Putative phosphoesterase; Similar to E. coli orf, hypothetical protein (AAC75360.1); Blastp hit to AAC75360.1 (184 aa), 85% identity in aa 2 - 183.
      
 0.718
STM4262
Putative ABC-type bacteriocin/lantibiotic exporter; Contains an N-terminal double-glycine peptidase domain; leukotoxin expression protein B homolog (gi|7467272).
      
 0.647
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
  
  
 0.620
cbpA
Curved DNA-binding protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
      
 0.607
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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