Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tesBSimilar to E. coli acyl-CoA thioesterase II (AAC73555.1); Blastp hit to AAC73555.1 (286 aa), 91% identity in aa 1 - 286. (286 aa)    
Predicted Functional Partners:
tesA
Similar to E. coli acyl-CoA thioesterase I; also functions as protease I (AAC73596.1); Blastp hit to AAC73596.1 (208 aa), 89% identity in aa 2 - 205.
      
 0.922
ybaW
Putative esterase; Similar to E. coli orf, hypothetical protein (AAC73546.1); Blastp hit to AAC73546.1 (132 aa), 94% identity in aa 1 - 132.
     
 0.896
ydiO
Putative acyl-CoA dehydrogenase; Similar to E. coli putative oxidoreductase (AAC74765.1); Blastp hit to AAC74765.1 (401 aa), 95% identity in aa 19 - 401.
   
 
 0.835
plsB
Glycerolphosphate acyltransferase activity; Similar to E. coli glycerol-3-phosphate acyltransferase (AAC77011.1); Blastp hit to AAC77011.1 (827 aa), 94% identity in aa 21 - 826; Belongs to the GPAT/DAPAT family.
 
  
 0.766
yqeF
Putative acetyl-CoA acetyltransferase; Similar to E. coli putative acyltransferase (AAC75883.1); Blastp hit to AAC75883.1 (394 aa), 91% identity in aa 2 - 393; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.724
fadB
3-hydroxyacyl-coA dehydrogenase of 4-enzyme FadB protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 
 
 0.697
yafH
Putative acyl-CoA dehydrogenase; Catalyzes the dehydrogenation of acyl-coenzymes A (acyl-CoAs) to 2-enoyl-CoAs, the first step of the beta-oxidation cycle of fatty acid degradation. Is required for S.typhimurium to utilize medium- and long-chain fatty acids as sole carbon sources for growth. Is needed for bacterial survival during carbone-source starvation.
   
 
 0.686
yciA
Putative Acyl-CoA hydrolase; Catalyzes the hydrolysis of the thioester bond in palmitoyl- CoA and malonyl-CoA.
   
  
 0.659
fadH
2,4-dieonyl-coa reductase; Similar to E. coli putative NADPH dehydrogenase (AAC76116.1); Blastp hit to AAC76116.1 (672 aa), 85% identity in aa 1 - 672.
  
  
 0.639
ybaY
Similar to E. coli glycoprotein/polysaccharide metabolism (AAC73556.1); Blastp hit to AAC73556.1 (190 aa), 88% identity in aa 1 - 190.
  
    0.611
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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