aefA protein (Salmonella enterica Typhimurium)

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aefA

Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117. (1120 aa)

Predicted Functional Partners:

recC

0.766

dacC

0.677

yecG

0.598

ycdZ

0.594

cysE

0.579

ybiH

0.569

acrR

0.559

hcr

0.525

cigR

0.471

menC

0.467

Your Current Organism:

Salmonella enterica Typhimurium

NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acrR	aefA	STM0477	STM0478	Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214.	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	0.559
aefA	acrR	STM0478	STM0477	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Similar to E. coli acrAB operon repressor (AAC73566.1); Blastp hit to AAC73566.1 (215 aa), 87% identity in aa 1 - 214.	0.559
aefA	cigR	STM0478	STM3762	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Putative inner membrane protein; Pathogenicity island encoded protein: SPI3; CigR (gi\|4324614).	0.471
aefA	cysE	STM0478	STM3699	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Serine acetyltransferase. (SW:CYSE_SALTY); Belongs to the transferase hexapeptide repeat family.	0.579
aefA	dacC	STM0478	STM0863	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Similar to E. coli D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6 (AAC73926.1); Blastp hit to AAC73926.1 (400 aa), 92% identity in aa 1 - 400; Belongs to the peptidase S11 family.	0.677
aefA	hcr	STM0478	STM0936	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	NADH oxidoreductase for hcp gene product; Similar to E. coli putative enzyme (AAC73959.1); Blastp hit to AAC73959.1 (322 aa), 90% identity in aa 1 - 322.	0.525
aefA	menC	STM0478	STM2306	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	o-succinylbenzoyl-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).	0.467
aefA	recC	STM0478	STM2996	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Exonuclease V, subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzy [...]	0.766
aefA	ybiH	STM0478	STM0819	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli putative transcriptional regulator (AAC73883.1); Blastp hit to AAC73883.1 (227 aa), 85% identity in aa 5 - 227.	0.569
aefA	ycdZ	STM0478	STM1138	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Putative inner membrane protein; Hypothetical protein in phoH-csgG intergenic region. (SW:YCDZ_SALTY).	0.594
aefA	yecG	STM0478	STM1927	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	Putative universal stress protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.	0.598
cigR	aefA	STM3762	STM0478	Putative inner membrane protein; Pathogenicity island encoded protein: SPI3; CigR (gi\|4324614).	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	0.471
cysE	aefA	STM3699	STM0478	Serine acetyltransferase. (SW:CYSE_SALTY); Belongs to the transferase hexapeptide repeat family.	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	0.579
dacC	aefA	STM0863	STM0478	Similar to E. coli D-alanyl-D-alanine carboxypeptidase; penicillin-binding protein 6 (AAC73926.1); Blastp hit to AAC73926.1 (400 aa), 92% identity in aa 1 - 400; Belongs to the peptidase S11 family.	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	0.677
hcr	aefA	STM0936	STM0478	NADH oxidoreductase for hcp gene product; Similar to E. coli putative enzyme (AAC73959.1); Blastp hit to AAC73959.1 (322 aa), 90% identity in aa 1 - 322.	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	0.525
hcr	ybiH	STM0936	STM0819	NADH oxidoreductase for hcp gene product; Similar to E. coli putative enzyme (AAC73959.1); Blastp hit to AAC73959.1 (322 aa), 90% identity in aa 1 - 322.	Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli putative transcriptional regulator (AAC73883.1); Blastp hit to AAC73883.1 (227 aa), 85% identity in aa 5 - 227.	0.423
hcr	ycdZ	STM0936	STM1138	NADH oxidoreductase for hcp gene product; Similar to E. coli putative enzyme (AAC73959.1); Blastp hit to AAC73959.1 (322 aa), 90% identity in aa 1 - 322.	Putative inner membrane protein; Hypothetical protein in phoH-csgG intergenic region. (SW:YCDZ_SALTY).	0.648
menC	aefA	STM2306	STM0478	o-succinylbenzoyl-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).	Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117.	0.467
menC	ybiH	STM2306	STM0819	o-succinylbenzoyl-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).	Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli putative transcriptional regulator (AAC73883.1); Blastp hit to AAC73883.1 (227 aa), 85% identity in aa 5 - 227.	0.531
menC	ycdZ	STM2306	STM1138	o-succinylbenzoyl-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).	Putative inner membrane protein; Hypothetical protein in phoH-csgG intergenic region. (SW:YCDZ_SALTY).	0.642

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