STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tesASimilar to E. coli acyl-CoA thioesterase I; also functions as protease I (AAC73596.1); Blastp hit to AAC73596.1 (208 aa), 89% identity in aa 2 - 205. (204 aa)    
Predicted Functional Partners:
ybbP
Putative inner membrane protein; Similar to E. coli putative oxidoreductase (AAC73598.1); Blastp hit to AAC73598.1 (804 aa), 88% identity in aa 1 - 804.
 
 
   0.970
ybbA
Putative ABC superfamily (atp_bind) transporter; Similar to E. coli putative ATP-binding component of a transport system (AAC73597.1); Blastp hit to AAC73597.1 (228 aa), 92% identity in aa 1 - 228.
 
   0.937
tesB
Similar to E. coli acyl-CoA thioesterase II (AAC73555.1); Blastp hit to AAC73555.1 (286 aa), 91% identity in aa 1 - 286.
      
 0.922
ybbO
Similar to E. coli putative oxidoreductase (AAC73595.1); Blastp hit to AAC73595.1 (269 aa), 90% identity in aa 14 - 268.
 
  
 0.896
ybbN
Similar to E. coli putative thioredoxin-like protein (AAC73594.1); Blastp hit to AAC73594.1 (296 aa), 94% identity in aa 13 - 296.
 
    0.794
ybaW
Putative esterase; Similar to E. coli orf, hypothetical protein (AAC73546.1); Blastp hit to AAC73546.1 (132 aa), 94% identity in aa 1 - 132.
   
  
 0.778
ydiO
Putative acyl-CoA dehydrogenase; Similar to E. coli putative oxidoreductase (AAC74765.1); Blastp hit to AAC74765.1 (401 aa), 95% identity in aa 19 - 401.
      
 0.725
fadR
Negative regulator of fad regulon; Multifunctional regulator of fatty acid metabolism. Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE. Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the glyoxylate shunt enzymes. Binding of FadR is specifically inhibited by long chain fatty acyl-CoA compounds (By similarity).
      
 0.723
plsB
Glycerolphosphate acyltransferase activity; Similar to E. coli glycerol-3-phosphate acyltransferase (AAC77011.1); Blastp hit to AAC77011.1 (827 aa), 94% identity in aa 21 - 826; Belongs to the GPAT/DAPAT family.
      
 0.697
aas
2-acylglycerophospho-ethanolamine acyl transferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
  
  
 0.689
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (66%) [HD]