Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
allAUreidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (160 aa)    
Predicted Functional Partners:
gcl
Similar to E. coli glyoxylate carboligase (AAC73609.1); Blastp hit to AAC73609.1 (593 aa), 96% identity in aa 1 - 593; Belongs to the TPP enzyme family.
 
 
 0.988
allD
Similar to E. coli putative malate dehydrogenase (AAC73619.1); Blastp hit to AAC73619.1 (349 aa), 86% identity in aa 1 - 349; Belongs to the LDH2/MDH2 oxidoreductase family.
   
 
 0.985
ylbA
Putative glyoxylate utilization; Similar to E. coli orf, hypothetical protein (AAC73617.1); Blastp hit to AAC73617.1 (261 aa), 92% identity in aa 1 - 261.
 
 
 0.981
allR
Putative regulatory protein; Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
  
  
 0.958
allC
Allantoate amidohydrolase; Similar to E. coli putative hydantoin utilization protein (AAC73618.1); Blastp hit to AAC73618.1 (411 aa), 88% identity in aa 1 - 411.
  
  
 0.918
allB
Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
  
  
 0.909
ybbS
Putative LysR family transcriptional regulator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter (By similarity).
  
  
 0.877
garR
Tartronate semialdehyde reductase (TSAR); Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
   
  
 0.860
aceB
Similar to E. coli malate synthase A (AAC76984.1); Blastp hit to AAC76984.1 (533 aa), 90% identity in aa 1 - 533.
    
 0.858
STM2959
Putative glycerate kinase 2; Similar to E. coli orf, hypothetical protein (AAC76158.1); Blastp hit to AAC76158.1 (408 aa), 68% identity in aa 28 - 405; Belongs to the glycerate kinase type-1 family.
      
 0.854
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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