STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
allRPutative regulatory protein; Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS-allA intergenic region (By similarity). (272 aa)    
Predicted Functional Partners:
allA
Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
  
  
 0.931
STM2668
Putative cytoplasmic protein.
      0.842
gcl
Similar to E. coli glyoxylate carboligase (AAC73609.1); Blastp hit to AAC73609.1 (593 aa), 96% identity in aa 1 - 593; Belongs to the TPP enzyme family.
  
  
 0.595
gip
Similar to E. coli glyoxylate-induced protein (AAC73610.1); Blastp hit to AAC73610.1 (258 aa), 84% identity in aa 1 - 258; Belongs to the hyi family.
  
    0.592
ybiJ
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73889.1); Blastp hit to AAC73889.1 (86 aa), 80% identity in aa 1 - 86.
      
 0.580
artP
Arginine transport system; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of 3rd arginine transport system (AAC73951.1); Blastp hit to AAC73951.1 (242 aa), 95% identity in aa 1 - 242.
   
  
 0.578
eco
Ecotin; General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
      
 0.578
ybgJ
Similar to E. coli putative carboxylase (AAC73805.1); Blastp hit to AAC73805.1 (218 aa), 86% identity in aa 1 - 218.
  
    0.534
ybgK
Similar to E. coli putative carboxylase (AAC73806.1); Blastp hit to AAC73806.1 (310 aa), 84% identity in aa 1 - 310.
  
    0.516
purR
Transcriptional repressor for pur regulon, glyA, glnB, prsA, speA (GalR/LacI family); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
      
 0.497
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.