STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fimIFimbrial protein internal segment; Fimbrin-like protein FIMI. (SW:FIMI_SALTY). (177 aa)    
Predicted Functional Partners:
fimC
Periplasmic chaperone, required for type 1 fimbriae; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH; Belongs to the periplasmic pilus chaperone family.
 
 
 0.989
fimF
Fimbrial-like protein FIMF precursor. (SW:FIMF_SALTY).
  
  
 0.982
fimH
Minor fimbrial subunit; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin (By similarity). Belongs to the fimbrial protein family.
  
  
 0.967
fimD
Outer membrane usher protein; Involved in the export and assembly of FimA fimbrial subunits across the outer membrane; Belongs to the fimbrial export usher family.
  
 
 0.914
fimA
Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs; Belongs to the fimbrial protein family.
  
  
0.888
fimZ
Fimbrial protein Z; Putative transcriptional regulator (LuxR/UhpA family); fimbriae Z protein. (SW:FIMZ_SALTY).
   
  
 0.860
fimW
Putative fimbrial protein; Fimbriae W protein. (SW:FIMW_SALTY).
   
  
 0.859
fimY
Putative regulatory protein; Fimbriae Y protein. (SW:FIMY_SALTY).
   
  
 0.856
STM0551
Putative diguanylate cyclase/phosphodiesterase domain 0.
      
 0.723
stcC
Similar to E. coli putative outer membrane protein (AAC75170.1); Blastp hit to AAC75170.1 (826 aa), 74% identity in aa 1 - 826.
   
 
 0.446
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.