STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fimCPeriplasmic chaperone, required for type 1 fimbriae; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH; Belongs to the periplasmic pilus chaperone family. (230 aa)    
Predicted Functional Partners:
fimH
Minor fimbrial subunit; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin (By similarity). Belongs to the fimbrial protein family.
  
 
 0.994
fimI
Fimbrial protein internal segment; Fimbrin-like protein FIMI. (SW:FIMI_SALTY).
 
 
 0.991
fimF
Fimbrial-like protein FIMF precursor. (SW:FIMF_SALTY).
  
 
 0.991
fimD
Outer membrane usher protein; Involved in the export and assembly of FimA fimbrial subunits across the outer membrane; Belongs to the fimbrial export usher family.
 
 
 0.987
fimA
Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs; Belongs to the fimbrial protein family.
 
 
 0.979
stbC
Putative fimbriae; Similar to E. coli outer membrane protein; export and assembly of type 1 fimbriae, interrupted (AAC77273.1); Blastp hit to AAC77273.1 (878 aa), 30% identity in aa 30 - 870.
  
 
 0.907
sthB
Similar to E. coli putative outer membrane protein, export function (AAC73634.1); Blastp hit to AAC73634.1 (867 aa), 38% identity in aa 35 - 862.
 
 
 0.902
lpfC
Long polar fimbrial outer membrane usher protein; Involved in the export and assembly of LpfA fimbrial subunits across the outer membrane; Belongs to the fimbrial export usher family.
  
 
 0.891
bcfC
Fimbrial usher; Bovine colonization factor BcfC (gi|4530570).
  
 
 0.873
stiC
Putative fimbrial usher; Similar to E. coli putative outer membrane protein (AAC76178.1); Blastp hit to AAC76178.1 (838 aa), 39% identity in aa 20 - 558, 34% identity in aa 493 - 837.
  
 
 0.873
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.