close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fimHMinor fimbrial subunit; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin (By similarity). Belongs to the fimbrial protein family. (335 aa)    
Predicted Functional Partners:
fimF
Fimbrial-like protein FIMF precursor. (SW:FIMF_SALTY).
  
  
 0.998
fimC
Periplasmic chaperone, required for type 1 fimbriae; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH; Belongs to the periplasmic pilus chaperone family.
  
 
 0.994
fimA
Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs; Belongs to the fimbrial protein family.
     
 0.992
fimI
Fimbrial protein internal segment; Fimbrin-like protein FIMI. (SW:FIMI_SALTY).
  
  
 0.985
fimD
Outer membrane usher protein; Involved in the export and assembly of FimA fimbrial subunits across the outer membrane; Belongs to the fimbrial export usher family.
  
 
 0.971
fliC
Flagellar biosynthesis; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
      
 0.928
ybbS
Putative LysR family transcriptional regulator; Positive regulator essential for the expression of allD operon. Binds to the allD promoter (By similarity).
   
  
 0.896
sitA
Fur regulated Salmonella iron transporter; SitA (gi|5231094); Belongs to the bacterial solute-binding protein 9 family.
      
 0.893
csgA
Curlin major subunit; Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin; Belongs to the CsgA/CsgB family.
      
 0.892
fimW
Putative fimbrial protein; Fimbriae W protein. (SW:FIMW_SALTY).
   
  
 0.809
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.