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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fimYPutative regulatory protein; Fimbriae Y protein. (SW:FIMY_SALTY). (240 aa)    
Predicted Functional Partners:
STM0551
Putative diguanylate cyclase/phosphodiesterase domain 0.
  
  
 0.983
fimW
Putative fimbrial protein; Fimbriae W protein. (SW:FIMW_SALTY).
  
  
 0.977
fimZ
Fimbrial protein Z; Putative transcriptional regulator (LuxR/UhpA family); fimbriae Z protein. (SW:FIMZ_SALTY).
   
 
 0.958
fimA
Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs; Belongs to the fimbrial protein family.
   
  
 0.899
fimI
Fimbrial protein internal segment; Fimbrin-like protein FIMI. (SW:FIMI_SALTY).
   
  
 0.894
fimF
Fimbrial-like protein FIMF precursor. (SW:FIMF_SALTY).
   
  
 0.836
fimH
Minor fimbrial subunit; Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin (By similarity). Belongs to the fimbrial protein family.
   
  
 0.769
fimC
Periplasmic chaperone, required for type 1 fimbriae; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH; Belongs to the periplasmic pilus chaperone family.
   
  
 0.765
STM0347
Putative response regulator; Unknown (gi|6707275).
   
  
 0.704
lpfB
Long polar fimbrial chaperone; Required for the biogenesis of long polar fimbria; binds and interact with LpfA; Belongs to the periplasmic pilus chaperone family.
   
  
 0.675
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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