Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM0551Putative diguanylate cyclase/phosphodiesterase domain 0. (103 aa)    
Predicted Functional Partners:
fimY
Putative regulatory protein; Fimbriae Y protein. (SW:FIMY_SALTY).
  
  
 0.974
fimW
Putative fimbrial protein; Fimbriae W protein. (SW:FIMW_SALTY).
  
  
 0.943
fimZ
Fimbrial protein Z; Putative transcriptional regulator (LuxR/UhpA family); fimbriae Z protein. (SW:FIMZ_SALTY).
   
  
 0.898
STM0286
Putative cytoplasmic protein.
      
 0.852
fimA
Major type 1 subunit fimbrin (pilin); Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs; Belongs to the fimbrial protein family.
      
 0.726
fimC
Periplasmic chaperone, required for type 1 fimbriae; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH; Belongs to the periplasmic pilus chaperone family.
      
 0.725
fimI
Fimbrial protein internal segment; Fimbrin-like protein FIMI. (SW:FIMI_SALTY).
      
 0.723
fimF
Fimbrial-like protein FIMF precursor. (SW:FIMF_SALTY).
   
  
 0.722
STM2010
Putative cytoplasmic protein.
      
 0.717
STM3356
Putative cation transporter; Similar to E. coli putative transport protein (AAC75352.1); Blastp hit to AAC75352.1 (610 aa), 38% identity in aa 9 - 199, 34% identity in aa 441 - 610, 23% identity in aa 35 - 196, 22% identity in aa 425 - 594.
      
 0.678
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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