Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nfnBDihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). (217 aa)    
Predicted Functional Partners:
mdaA
Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product.
     
 0.996
nemA
Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365.
 
 
 0.921
ybdF
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73680.1); Blastp hit to AAC73680.1 (122 aa), 75% identity in aa 1 - 121.
     
 0.786
ycaO
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589.
  
  
 0.606
STM0580
Putative regulatory protein.
 
   
 0.604
yhiH
Putative ABC-type multidrug transport system; ATPase component; Permease component of an ABC-transporter; similar to E. coli putative ATP-binding component of a transport system, fragment 1 (AAC76511.1); Blastp hit to AAC76511.1 (894 aa), 89% identity in aa 1 - 894.
  
  
 0.594
birA
biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.592
ybjX
Homolog of virK; Similar to E. coli putative enzyme (AAC73964.1); Blastp hit to AAC73964.1 (330 aa), 57% identity in aa 15 - 329.
  
    0.536
gltB
Similar to E. coli glutamate synthase, large subunit (AAC76244.1); Blastp hit to AAC76244.1 (1517 aa), 95% identity in aa 32 - 1517.
     
 0.497
yfhC
Putative cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
 0.486
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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