Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fepESimilar to E. coli ferric enterobactin (enterochelin) transport (AAC73688.1); Blastp hit to AAC73688.1 (377 aa), 73% identity in aa 1 - 373. (378 aa)    
Predicted Functional Partners:
fes
Similar to E. coli enterochelin esterase (AAC73686.1); Blastp hit to AAC73686.1 (374 aa), 74% identity in aa 2 - 369.
  
  
 0.781
entD
Enterochelin synthetase, component D (phoshpantetheinyltransferase); Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3- dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo- domains of both EntB (ArCP domain) and EntF (PC [...]
  
  
 0.757
entF
Enterobactin synthetase, component F (nonribosomal peptide synthetase); Similar to E. coli ATP-dependent serine activating enzyme (may be part of enterobactin synthase as component F) (AAC73687.1); Blastp hit to AAC73687.1 (1293 aa), 79% identity in aa 1 - 1293.
     
 0.730
fepG
Ferric enterobactin transporter; ABC superfamily (membrane); similar to E. coli ferric enterobactin transport protein (AAC73690.1); Blastp hit to AAC73690.1 (330 aa), 86% identity in aa 2 - 330; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
   
  
 0.728
fepB
ABC superfamily (peri_perm); similar to E. coli ferric enterobactin (enterochelin) binding protein; periplasmic component (AAC73693.1); Blastp hit to AAC73693.1 (318 aa), 79% identity in aa 1 - 318.
   
  
 0.701
yjgN
Putative inner membrane protein; Hypothetical protein in miaE 3'region (ORF x). (SW:YJGN_SALTY).
      
 0.701
entA
Similar to E. coli 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis (AAC73697.1); Blastp hit to AAC73697.1 (248 aa), 90% identity in aa 2 - 248.
   
  
 0.682
fepD
ABC superfamily (membrane); similar to E. coli ferric enterobactin (enterochelin) transport (AAC73691.1); Blastp hit to AAC73691.1 (334 aa), 88% identity in aa 1 - 333; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
      
 0.677
fepC
Enterobactin transporter; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of ferric enterobactin transport (AAC73689.1); Blastp hit to AAC73689.1 (271 aa), 92% identity in aa 1 - 263.
      
 0.650
entC
Similar to E. coli isochorismate hydroxymutase 2, enterochelin biosynthesis (AAC73694.1); Blastp hit to AAC73694.1 (391 aa), 84% identity in aa 1 - 391.
   
  
 0.616
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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