STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cstASimilar to E. coli carbon starvation protein (AAC73699.1); Blastp hit to AAC73699.1 (701 aa), 97% identity in aa 1 - 701. (701 aa)    
Predicted Functional Partners:
ybdD
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77309.1); Blastp hit to AAC77309.1 (67 aa), 73% identity in aa 1 - 67.
 
    0.955
yjiX
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77309.1); Blastp hit to AAC77309.1 (67 aa), 94% identity in aa 1 - 67.
  
 0.906
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
   
  
 0.897
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
      
 0.757
sbmA
Putative ABC superfamily transporter; Similar to E. coli sensitivity to microcin B17, possibly envelop protein (AAC73480.1); Blastp hit to AAC73480.1 (406 aa), 92% identity in aa 1 - 406.
      
 0.700
putP
SSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.650
putA
Plasma membrane proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
  
 0.572
hfq
Host factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells.
      
 0.567
STM1128
Similar to E. coli putative cotransporter (AAC76702.1); Blastp hit to AAC76702.1 (571 aa), 22% identity in aa 7 - 478; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
    0.534
entB
Similar to E. coli 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase (AAC73696.1); Blastp hit to AAC73696.1 (285 aa), 88% identity in aa 1 - 285.
  
    0.533
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.