STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybdMPutative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC73702.1); Blastp hit to AAC73702.1 (209 aa), 77% identity in aa 5 - 209. (205 aa)    
Predicted Functional Partners:
ybdN
Putative 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; Similar to E. coli orf, hypothetical protein (AAC73703.1); Blastp hit to AAC73703.1 (406 aa), 82% identity in aa 1 - 406.
 
 
 0.988
yhjQ
Putative ATPase involved in chromosome partitioning; Essential for cellulose biosynthesis. May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity); Belongs to the BcsQ family.
  
 
 0.873
gidB
Associated with glucose-inhibited division; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
  
 0.760
ftsZ
Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.521
ybdO
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73704.1); Blastp hit to AAC73704.1 (300 aa), 54% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family.
  
    0.501
topA
DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...]
  
  
 0.481
lepB
Leader peptidase (signal peptidase I), serine protease; Signal peptidase I. (SW:LEP_SALTY); Belongs to the peptidase S26 family.
  
  
 0.472
glpB
Sn-glycerol-3-phosphate dehydrogenase (anaerobic), membrane anchor subunit; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor; Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
  
     0.451
dsbG
Periplasmic disulfide isomerase, thiol-disulphide oxidase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
   
 0.418
caiB
L-carnitine dehydratase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity); Belongs to the CoA-transferase III family. CaiB subfamily.
  
     0.404
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.