Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM0613Putative hydrogenase protein; Similar to E. coli putative DMSO reductase anchor subunit (AAC74662.1); Blastp hit to AAC74662.1 (284 aa), 30% identity in aa 6 - 200. (255 aa)    
Predicted Functional Partners:
dmsC
Similar to E. coli anaerobic dimethyl sulfoxide reductase subunit C (AAC73982.1); Blastp hit to AAC73982.1 (287 aa), 89% identity in aa 1 - 287.
  
 
 0.973
STM4307
Putative anaerobic dimethyl sulfoxide reductase, subunit C; Similar to E. coli putative DMSO reductase anchor subunit (AAC74662.1); Blastp hit to AAC74662.1 (284 aa), 34% identity in aa 6 - 274.
  
  
 0.970
STM0610
Putative component of anaerobic dehydrogenases; Similar to E. coli putative oxidoreductase component (AAC74663.1); Blastp hit to AAC74663.1 (207 aa), 30% identity in aa 78 - 196.
 
  
 0.946
STM0611
Similar to E. coli putative oxidoreductase, major subunit (AAC74659.1); Blastp hit to AAC74659.1 (808 aa), 31% identity in aa 10 - 314, 26% identity in aa 298 - 673, 36% identity in aa 636 - 765, 34% identity in aa 489 - 517; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   0.936
STM1496
Similar to E. coli putative DMSO reductase anchor subunit (AAC74662.1); Blastp hit to AAC74662.1 (284 aa), 76% identity in aa 1 - 284.
  
  
 
0.928
STM2528
Putative dimethylsulfoxide reductase; Similar to E. coli anaerobic dimethyl sulfoxide reductase subunit C (AAC73982.1); Blastp hit to AAC73982.1 (287 aa), 32% identity in aa 6 - 277.
  
  
 
0.928
hycG
Similar to E. coli hydrogenase activity (AAC75761.1); Blastp hit to AAC75761.1 (255 aa), 96% identity in aa 1 - 255.
      
 0.897
hycE
Part of FHL complex; similar to E. coli large subunit of hydrogenase 3 (part of FHL complex) (AAC75763.1); Blastp hit to AAC75763.1 (569 aa), 97% identity in aa 1 - 569.
     
 0.861
hypB
Hydrogenase-3 accessory protein; Assembly of metallocenter; similar to E. coli guanine-nucleotide binding protein, functions as nickel donor for large subunit of hydrogenase 3 (AAC75769.1); Blastp hit to AAC75769.1 (290 aa), 94% identity in aa 1 - 290.
      
 0.860
hypF
Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
   
  
 0.845
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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