STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnaSimilar to E. coli RNase I, cleaves phosphodiester bond between any two nucleotides (AAC73712.1); Blastp hit to AAC73712.1 (268 aa), 73% identity in aa 1 - 268; Belongs to the RNase T2 family. (268 aa)    
Predicted Functional Partners:
ybhC
Similar to E. coli putative pectinesterase (AAC73859.1); Blastp hit to AAC73859.1 (427 aa), 86% identity in aa 1 - 427.
  
     0.768
hfq
Host factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells.
   
  
 0.760
usg
Putative aspartate-semialdehyde dehydrogenase; Similar to E. coli putative PTS system enzyme II A component (AAC75379.1); Blastp hit to AAC75379.1 (337 aa), 89% identity in aa 1 - 337; Belongs to the aspartate-semialdehyde dehydrogenase family.
      
 0.715
rnc
RNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Removes small helical intervening sequences (IVSs) from all 7 of the 23S rRNA transcripts. Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
      
 0.674
wcaC
Putative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative glycosyl transferase (AAC75118.1); Blastp hit to AAC75118.1 (405 aa), 80% identity in aa 1 - 405.
  
     0.660
citX
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73715.1); Blastp hit to AAC73715.1 (183 aa), 75% identity in aa 1 - 179.
     
 0.653
bglJ
Transcriptional regulator (activator) of bgl operon; LuxR/UhpA family; similar to E. coli 2-component transcriptional regulator (AAC77322.1); Blastp hit to AAC77322.1 (225 aa), 63% identity in aa 1 - 223.
  
     0.612
ybiO
Similar to E. coli putative transport protein (AAC73895.1); Blastp hit to AAC73895.1 (786 aa), 85% identity in aa 46 - 786.
  
     0.610
wcaA
Putative glycosyl transferase; In colanic acid gene cluster; similar to E. coli putative regulator (AAC75120.1); Blastp hit to AAC75120.1 (279 aa), 91% identity in aa 3 - 279.
  
     0.572
yfeO
Putative chloride channel permease; Similar to E. coli orf, hypothetical protein (AAC75448.1); Blastp hit to AAC75448.1 (418 aa), 80% identity in aa 1 - 408.
  
     0.556
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.