| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acpT | crcB | STM3583 | STM0630 | Putative phosphopantetheinyl transferase; May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis. The native apo- protein substrate is unknown; Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.699 |
| acpT | lipA | STM3583 | STM0633 | Putative phosphopantetheinyl transferase; May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis. The native apo- protein substrate is unknown; Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. | Lipoate synthase, an iron-sulfur enzyme; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.466 |
| acpT | udk | STM3583 | STM2122 | Putative phosphopantetheinyl transferase; May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis. The native apo- protein substrate is unknown; Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. | Similar to E. coli uridine/cytidine kinase (AAC75127.1); Blastp hit to AAC75127.1 (231 aa), 95% identity in aa 19 - 231. | 0.457 |
| acpT | ybeC | STM3583 | STM0632 | Putative phosphopantetheinyl transferase; May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis. The native apo- protein substrate is unknown; Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.455 |
| crcB | acpT | STM0630 | STM3583 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Putative phosphopantetheinyl transferase; May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis. The native apo- protein substrate is unknown; Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. | 0.699 |
| crcB | hemF | STM0630 | STM2451 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.550 |
| crcB | hemL | STM0630 | STM0202 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Glutamate-1-semialdehyde 2,1-aminomutase. (SW:GSA_SALTY). | 0.438 |
| crcB | kup | STM0630 | STM3880 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | KUP family low affinity potassium transport system; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family. | 0.459 |
| crcB | lipA | STM0630 | STM0633 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Lipoate synthase, an iron-sulfur enzyme; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.624 |
| crcB | udk | STM0630 | STM2122 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Similar to E. coli uridine/cytidine kinase (AAC75127.1); Blastp hit to AAC75127.1 (231 aa), 95% identity in aa 19 - 231. | 0.573 |
| crcB | yadQ | STM0630 | STM0203 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Putative ClC family chlorine transport protein; Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. | 0.718 |
| crcB | ybaX | STM0630 | STM0455 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Putative (aluminum) resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.651 |
| crcB | ybeC | STM0630 | STM0632 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.818 |
| crcB | ybeM | STM0630 | STM0631 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Similar to E. coli putative amidase (AAC73727.1); Blastp hit to AAC73727.1 (187 aa), 77% identity in aa 2 - 187. | 0.557 |
| hemF | crcB | STM2451 | STM0630 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.550 |
| hemF | hemL | STM2451 | STM0202 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Glutamate-1-semialdehyde 2,1-aminomutase. (SW:GSA_SALTY). | 0.731 |
| hemF | lipA | STM2451 | STM0633 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Lipoate synthase, an iron-sulfur enzyme; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.452 |
| hemF | udk | STM2451 | STM2122 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Similar to E. coli uridine/cytidine kinase (AAC75127.1); Blastp hit to AAC75127.1 (231 aa), 95% identity in aa 19 - 231. | 0.418 |
| hemF | ybeC | STM2451 | STM0632 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.503 |
| hemL | crcB | STM0202 | STM0630 | Glutamate-1-semialdehyde 2,1-aminomutase. (SW:GSA_SALTY). | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.438 |