| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| crcB | ybeC | STM0630 | STM0632 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.743 |
| crcB | ybeM | STM0630 | STM0631 | High-copy crc-csp restores normal chromosome condensation in presence of camphor or mukB mutations; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Similar to E. coli putative amidase (AAC73727.1); Blastp hit to AAC73727.1 (187 aa), 77% identity in aa 2 - 187. | 0.557 |
| guaA | tatA | STM2510 | STM3973 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.885 |
| guaA | tatB | STM2510 | STM3974 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.885 |
| guaA | tatC | STM2510 | STM3975 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.517 |
| guaA | ybeC | STM2510 | STM0632 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.885 |
| secD | tatA | STM0407 | STM3973 | Preprotein translocase, IISP family, part of the channel; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.700 |
| secD | tatB | STM0407 | STM3974 | Preprotein translocase, IISP family, part of the channel; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.782 |
| secD | tatC | STM0407 | STM3975 | Preprotein translocase, IISP family, part of the channel; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.680 |
| secD | ybeC | STM0407 | STM0632 | Preprotein translocase, IISP family, part of the channel; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.680 |
| sspB | tatA | STM3341 | STM3973 | Similar to E. coli stringent starvation protein B (AAC76260.1); Blastp hit to AAC76260.1 (165 aa), 89% identity in aa 1 - 165. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.479 |
| sspB | ybeC | STM3341 | STM0632 | Similar to E. coli stringent starvation protein B (AAC76260.1); Blastp hit to AAC76260.1 (165 aa), 89% identity in aa 1 - 165. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.716 |
| tatA | guaA | STM3973 | STM2510 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.885 |
| tatA | secD | STM3973 | STM0407 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Preprotein translocase, IISP family, part of the channel; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.700 |
| tatA | sspB | STM3973 | STM3341 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Similar to E. coli stringent starvation protein B (AAC76260.1); Blastp hit to AAC76260.1 (165 aa), 89% identity in aa 1 - 165. | 0.479 |
| tatA | tatB | STM3973 | STM3974 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.999 |
| tatA | tatC | STM3973 | STM3975 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Component of sec-independent protein export; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.999 |
| tatA | ybeC | STM3973 | STM0632 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Putative Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. | 0.961 |
| tatA | yciI | STM3973 | STM1738 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74333.1); Blastp hit to AAC74333.1 (130 aa), 91% identity in aa 33 - 130. | 0.516 |
| tatA | yigW | STM3973 | STM3976 | Component of Sec-independent protein secretion pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Putative hydrolase of PHP superfamily; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. | 0.919 |
