STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybeDPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73732.1); Blastp hit to AAC73732.1 (87 aa), 97% identity in aa 1 - 87; Belongs to the UPF0250 family. (87 aa)    
Predicted Functional Partners:
phoL
Putative phosphate starvation-inducible protein, ATP-binding; Similar to E. coli putative ATP-binding protein in pho regulon (AAC73761.1); Blastp hit to AAC73761.1 (359 aa), 96% identity in aa 1 - 359.
  
  
 0.924
lipB
Putative ligase in lipoate biosynthesis; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
  
 0.916
yhaL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76142.1); Blastp hit to AAC76142.1 (56 aa), 70% identity in aa 3 - 56.
      
 0.892
yhiR
Putative cytoplasmic protein; Specifically methylates the adenine in position 2030 of 23S rRNA.
      
 0.808
yheM
Putative oxidation of intracellular sulfur; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
  
   
 0.806
ycaR
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74003.1); Blastp hit to AAC74003.1 (60 aa), 93% identity in aa 1 - 60; Belongs to the UPF0434 family.
   
  
 0.798
fxsA
Suppresses F exclusion of bacteriophage T7; Similar to E. coli orf, hypothetical protein (AAC77100.1); Blastp hit to AAC77100.1 (125 aa), 92% identity in aa 1 - 125.
 
  
 0.787
yigP
Putative inner membrane protein; Required for ubiquinone (coenzyme Q) biosynthesis under aerobic conditions. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex (By similarity). May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates (By similarity). Required for intracellular proliferation in macrophages. Belongs to the UbiJ family.
  
   
 0.786
yheN
Putative ACR involved in intracellular sulfur reduction; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
      
 0.754
ybaB
Putative cytoplasmic protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
   
  
 0.752
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.