Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gltIGlutamate/aspartate transporter; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate. (308 aa)    
Predicted Functional Partners:
gltJ
Glutamate/aspartate transporter; ABC superfamily (membrane); similar to E. coli glutamate/aspartate transport system permease (AAC73755.1); Blastp hit to AAC73755.1 (246 aa), 94% identity in aa 1 - 246.
 0.998
gltL
Glutamate/aspartate transporter; ABC superfamily (atp_bind); similar to E. coli ATP-binding protein of glutamate/aspartate transport system (AAC73753.1); Blastp hit to AAC73753.1 (241 aa), 95% identity in aa 1 - 241.
 
 0.996
gltK
Glutamate/aspartate transporter; ABC superfamily (membrane); similar to E. coli glutamate/aspartate transport system permease (AAC73754.1); Blastp hit to AAC73754.1 (224 aa), 95% identity in aa 1 - 223.
 0.993
oppA
Oligopeptide transport protein with chaperone properties; This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity; Belongs to the bacterial solute-binding protein 5 family.
   
  
 0.882
dppA
Dipeptide transport protein; ABC superfamily (peri_perm); similar to E. coli dipeptide transport protein (AAC76569.1); Blastp hit to AAC76569.1 (535 aa), 93% identity in aa 1 - 535.
   
  
 0.747
gltA
Citrate synthase. (SW:CISY_SALTY).
   
  
 0.745
STM0731
Putative inner membrane protein.
   
    0.742
sdhB
Succinate dehydrogenase, Fe-S protein; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
   
  
 0.671
acnB
Aconitate hydratase 2; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2- methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA- binding regulatory protein which regulates FliC synthesis via interaction with the ftsH transcript to decrease the intracellular levels of FtsH. The lower levels of Fts [...]
  
    0.634
yifK
Putative APC family amino-acid transport protein; Probable amino-acid or metabolite transport protein; Belongs to the amino acid-polyamine-organocation (APC) superfamily.
   
  
 0.614
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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