node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STM0402 | fur | STM0402 | STM0693 | Similar to E. coli alkyl hydroperoxide reductase, C22 subunit; detoxification of hydroperoxides (AAC73706.1); Blastp hit to AAC73706.1 (187 aa), 36% identity in aa 1 - 186. | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | 0.641 |
STM0402 | norV | STM0402 | STM2840 | Similar to E. coli alkyl hydroperoxide reductase, C22 subunit; detoxification of hydroperoxides (AAC73706.1); Blastp hit to AAC73706.1 (187 aa), 36% identity in aa 1 - 186. | Putative flavoprotein; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. | 0.584 |
STM0402 | trxA | STM0402 | STM3915 | Similar to E. coli alkyl hydroperoxide reductase, C22 subunit; detoxification of hydroperoxides (AAC73706.1); Blastp hit to AAC73706.1 (187 aa), 36% identity in aa 1 - 186. | Thioredoxin 1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family. | 0.616 |
STM1078 | fur | STM1078 | STM0693 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74051.1); Blastp hit to AAC74051.1 (164 aa), 91% identity in aa 27 - 164. | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | 0.544 |
ahpC | fur | STM0608 | STM0693 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | 0.647 |
ahpC | norV | STM0608 | STM2840 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Putative flavoprotein; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. | 0.636 |
ahpC | trxA | STM0608 | STM3915 | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Thioredoxin 1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family. | 0.807 |
feoB | fhuC | STM3506 | STM0192 | Ferrous iron transport protein B; Probable transporter for a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | Hydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. | 0.445 |
feoB | fur | STM3506 | STM0693 | Ferrous iron transport protein B; Probable transporter for a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | 0.631 |
fhuC | feoB | STM0192 | STM3506 | Hydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. | Ferrous iron transport protein B; Probable transporter for a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | 0.445 |
fhuC | fur | STM0192 | STM0693 | Hydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | 0.706 |
fldA | fur | STM0694 | STM0693 | Flavodoxin 1; Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase; Belongs to the flavodoxin family. | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | 0.868 |
fldA | ybfE | STM0694 | STM0695 | Flavodoxin 1; Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase; Belongs to the flavodoxin family. | LexA regulated, putative SOS response; Similar to E. coli orf, hypothetical protein (AAC73779.1); Blastp hit to AAC73779.1 (120 aa), 90% identity in aa 24 - 120. | 0.952 |
fur | STM0402 | STM0693 | STM0402 | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | Similar to E. coli alkyl hydroperoxide reductase, C22 subunit; detoxification of hydroperoxides (AAC73706.1); Blastp hit to AAC73706.1 (187 aa), 36% identity in aa 1 - 186. | 0.641 |
fur | STM1078 | STM0693 | STM1078 | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74051.1); Blastp hit to AAC74051.1 (164 aa), 91% identity in aa 27 - 164. | 0.544 |
fur | ahpC | STM0693 | STM0608 | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.647 |
fur | feoB | STM0693 | STM3506 | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | Ferrous iron transport protein B; Probable transporter for a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. | 0.631 |
fur | fhuC | STM0693 | STM0192 | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | Hydroxymate-dependent iron transport; ABC superfamily (atp_bind); similar to E. coli ATP-binding component of hydroxymate-dependent iron transport (AAC73262.1); Blastp hit to AAC73262.1 (265 aa), 92% identity in aa 1 - 265. | 0.706 |
fur | fldA | STM0693 | STM0694 | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | Flavodoxin 1; Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase; Belongs to the flavodoxin family. | 0.868 |
fur | menI | STM0693 | STM1366 | Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family. | Putative protein PaaI; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA). | 0.699 |