Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fldAFlavodoxin 1; Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase; Belongs to the flavodoxin family. (176 aa)    
Predicted Functional Partners:
ybfE
LexA regulated, putative SOS response; Similar to E. coli orf, hypothetical protein (AAC73779.1); Blastp hit to AAC73779.1 (120 aa), 90% identity in aa 24 - 120.
 
  
 0.950
STM2963
Putative MFS superfamily D-glucarate permease; Similar to E. coli orf, hypothetical protein (AAC75832.1); Blastp hit to AAC75832.1 (149 aa), 88% identity in aa 1 - 149.
      
 0.896
fur
Transcriptional repressor of iron-responsive genes (Fur family) (ferric uptake regulator); Similar to E. coli negative regulator (AAC73777.1); Blastp hit to AAC73777.1 (148 aa), 99% identity in aa 1 - 146; Belongs to the Fur family.
 
  
 0.895
btuR
cob(I)alamin and cobinamide adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids; Belongs to the Cob(I)alamin adenosyltransferase family.
      
 0.860
pduO
Propanediol utilization B12 related protein; Belongs to the Cob(I)alamin adenosyltransferase family.
      
 0.859
STM0691
Putative periplasmic protein.
   
 
 0.794
nifJ
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174.
 
   
 0.745
yjgP
Putative permease; Similar to E. coli orf, hypothetical protein (AAC77218.1); Blastp hit to AAC77218.1 (366 aa), 94% identity in aa 1 - 366.
   
  
 0.728
eutT
Putative ethanolamine utilization cobalamin adenosyltransferase; Converts CNB12 to ADOB12.
      
 0.724
seqA
Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
    0.604
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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