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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybgKSimilar to E. coli putative carboxylase (AAC73806.1); Blastp hit to AAC73806.1 (310 aa), 84% identity in aa 1 - 310. (310 aa)    
Predicted Functional Partners:
ybgJ
Similar to E. coli putative carboxylase (AAC73805.1); Blastp hit to AAC73805.1 (218 aa), 86% identity in aa 1 - 218.
 0.999
ybgL
Putative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
 0.999
ybgI
Putative cytoplasmic protein; Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides. Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
  
 0.972
accC
Acetyl CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
      0.912
ybdK
Putative cytoplasmic protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
     
  0.900
gshA
Glutamate--cysteine ligase. (SW:GSH1_SALTY); Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
ggt
Similar to E. coli gamma-glutamyltranspeptidase (AAC76472.1); Blastp hit to AAC76472.1 (580 aa), 91% identity in aa 2 - 580.
     
  0.900
gltB
Similar to E. coli glutamate synthase, large subunit (AAC76244.1); Blastp hit to AAC76244.1 (1517 aa), 95% identity in aa 32 - 1517.
   
 
  0.825
gdhA
NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
  
 
  0.822
putA
Plasma membrane proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
  0.821
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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