| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alkB | osmY | STM2264 | STM4561 | DNA repair system specific for alkylated DNA; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (B [...] | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | 0.649 |
| alkB | ybgS | STM2264 | STM0759 | DNA repair system specific for alkylated DNA; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (B [...] | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | 0.750 |
| alkB | ydjN | STM2264 | STM1320 | DNA repair system specific for alkylated DNA; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (B [...] | Kinase-like protein; Putative domain shared with transporter; similar to E. coli part of a kinase (AAC74799.1); Blastp hit to AAC74799.1 (463 aa), 96% identity in aa 1 - 462; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.450 |
| alkB | yjiJ | STM2264 | STM4515 | DNA repair system specific for alkylated DNA; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (B [...] | Putative sugar transporter; Similar to E. coli putative transport protein (AAC77288.1); Blastp hit to AAC77288.1 (392 aa), 72% identity in aa 3 - 386. | 0.874 |
| fxsA | ybgS | STM4327 | STM0759 | Suppresses F exclusion of bacteriophage T7; Similar to E. coli orf, hypothetical protein (AAC77100.1); Blastp hit to AAC77100.1 (125 aa), 92% identity in aa 1 - 125. | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | 0.818 |
| fxsA | ydjN | STM4327 | STM1320 | Suppresses F exclusion of bacteriophage T7; Similar to E. coli orf, hypothetical protein (AAC77100.1); Blastp hit to AAC77100.1 (125 aa), 92% identity in aa 1 - 125. | Kinase-like protein; Putative domain shared with transporter; similar to E. coli part of a kinase (AAC74799.1); Blastp hit to AAC74799.1 (463 aa), 96% identity in aa 1 - 462; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.579 |
| galM | ybgS | STM0773 | STM0759 | Galactose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer. | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | 0.602 |
| osmY | alkB | STM4561 | STM2264 | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | DNA repair system specific for alkylated DNA; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (B [...] | 0.649 |
| osmY | ybgS | STM4561 | STM0759 | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | 0.948 |
| osmY | ygaU | STM4561 | STM2795 | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | Putative LysM domain protein; Similar to E. coli orf, hypothetical protein (AAC75712.1); Blastp hit to AAC75712.1 (149 aa), 93% identity in aa 1 - 149. | 0.933 |
| osmY | yhbO | STM4561 | STM3269 | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | Putative intracellular proteinase; Similar to E. coli orf, hypothetical protein (AAC76187.1); Blastp hit to AAC76187.1 (186 aa), 94% identity in aa 15 - 186. | 0.707 |
| osmY | yjbJ | STM4561 | STM4240 | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77015.1); Blastp hit to AAC77015.1 (69 aa), 95% identity in aa 1 - 69; Belongs to the UPF0337 (CsbD) family. | 0.965 |
| osmY | yjiJ | STM4561 | STM4515 | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | Putative sugar transporter; Similar to E. coli putative transport protein (AAC77288.1); Blastp hit to AAC77288.1 (392 aa), 72% identity in aa 3 - 386. | 0.897 |
| ybgR | ybgS | STM0758 | STM0759 | Putative CDF family transport protein; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | 0.595 |
| ybgS | alkB | STM0759 | STM2264 | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | DNA repair system specific for alkylated DNA; Dioxygenase that repairs alkylated DNA and RNA containing 3- methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha- ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (B [...] | 0.750 |
| ybgS | fxsA | STM0759 | STM4327 | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | Suppresses F exclusion of bacteriophage T7; Similar to E. coli orf, hypothetical protein (AAC77100.1); Blastp hit to AAC77100.1 (125 aa), 92% identity in aa 1 - 125. | 0.818 |
| ybgS | galM | STM0759 | STM0773 | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | Galactose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer. | 0.602 |
| ybgS | osmY | STM0759 | STM4561 | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | RpoS-dependent stationary phase gene; similar to E. coli hyperosmotically inducible periplasmic protein (AAC77329.1); Blastp hit to AAC77329.1 (201 aa), 89% identity in aa 1 - 201. | 0.948 |
| ybgS | ybgR | STM0759 | STM0758 | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | Putative CDF family transport protein; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. | 0.595 |
| ybgS | ydjN | STM0759 | STM1320 | Similar to E. coli putative homeobox protein (AAC73840.1); Blastp hit to AAC73840.1 (126 aa), 78% identity in aa 1 - 126. | Kinase-like protein; Putative domain shared with transporter; similar to E. coli part of a kinase (AAC74799.1); Blastp hit to AAC74799.1 (463 aa), 96% identity in aa 1 - 462; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.853 |