Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (382 aa)    
Predicted Functional Partners:
galM
Galactose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer.
 0.999
galT
Galactose-1-phosphate uridylyltransferase. (SW:GAL7_SALTY).
 0.999
galE
UDP-galactose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
 
 
 0.998
galU
Similar to E. coli glucose-1-phosphate uridylyltransferase (AAC74318.1); Blastp hit to AAC74318.1 (302 aa), 97% identity in aa 1 - 302.
  
 
 0.973
yihR
Similar to E. coli putative aldose-1-epimerase (AAC76876.1); Blastp hit to AAC76876.1 (308 aa), 54% identity in aa 9 - 303.
  
 0.968
mrr
Similar to E. coli restriction of methylated adenine (AAC77307.1); Blastp hit to AAC77307.1 (304 aa), 77% identity in aa 1 - 304.
      
 0.961
rpsL
30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
      
 0.941
galF
Putative glucose-1-phosphate uridylyltransferase, non-catalytic subunit; May play a role in stationary phase survival; Belongs to the UDPGP type 2 family.
    
 0.711
araD
L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
     
 0.674
fhlA
Formate hydrogen-lyase transcriptional activator for fdhF, hyc and hyp operons; Required for induction of expression of the formate dehydrogenase H and hydrogenase-3 structural genes.
      
 0.637
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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