STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hutGFormimionoglutamate hydrolase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (313 aa)    
Predicted Functional Partners:
hutI
Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.998
hutC
Histidine utilization repressor; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 24% identity in aa 5 - 229.
 
  
 0.948
hutH
Histidine ammonia lyase; Belongs to the PAL/histidase family.
 
  
 0.934
putA
Plasma membrane proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.922
yacG
Putative cytoplasmic protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
      
 0.896
ybeK
Putative purine nucleoside hydrolase; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
   
  
 0.859
yehX
Putative ABC-type proline/glycine betaine transport system, ATPase component; Similar to E. coli putative ATP-binding component of a transport system (AAC75190.1); Blastp hit to AAC75190.1 (308 aa), 87% identity in aa 1 - 307.
      
 0.854
gdhA
NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
  
 
 0.844
yneH
Similar to E. coli putative glutaminase (AAC74597.1); Blastp hit to AAC74597.1 (308 aa), 91% identity in aa 1 - 308; Belongs to the glutaminase family.
  
  
  0.844
STM1795
Putative homolog of glutamic dehydrogenase; Similar to E. coli NADP-specific glutamate dehydrogenase (AAC74831.1); Blastp hit to AAC74831.1 (447 aa), 32% identity in aa 33 - 408; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.844
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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