STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybhPPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73877.1); Blastp hit to AAC73877.1 (253 aa), 86% identity in aa 1 - 253. (252 aa)    
Predicted Functional Partners:
ybhN
Putative negative regulator; Similar to E. coli orf, hypothetical protein (AAC73875.1); Blastp hit to AAC73875.1 (318 aa), 89% identity in aa 1 - 318.
  
 0.990
ybhO
Cardiolipin (CL) synthase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
    0.977
ygiM
Putative SH3 domain protein; Similar to E. coli orf, hypothetical protein (AAC76091.1); Blastp hit to AAC76091.1 (206 aa), 91% identity in aa 1 - 206.
      
 0.860
perM
Similar to E. coli putative permease (AAC75546.1); Blastp hit to AAC75546.1 (353 aa), 94% identity in aa 1 - 350.
      
 0.854
poxB
Pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors, cytoplasmic in absence of cofactors; Similar to E. coli pyruvate oxidase (AAC73958.1); Blastp hit to AAC73958.1 (572 aa), 94% identity in aa 1 - 572; Belongs to the TPP enzyme family.
   
    0.727
yfcG
Similar to E. coli putative S-transferase (AAC75362.1); Blastp hit to AAC75362.1 (215 aa), 83% identity in aa 1 - 208.
   
    0.691
yibF
Similar to E. coli putative S-transferase (AAC76616.1); Blastp hit to AAC76616.1 (202 aa), 86% identity in aa 1 - 202.
  
    0.577
sufS
Selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
    
   0.546
csdA
Putative selenocysteine lyase; Similar to E. coli orf, hypothetical protein (AAC75852.1); Blastp hit to AAC75852.1 (401 aa), 89% identity in aa 1 - 401.
    
   0.546
ybhQ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC73878.1); Blastp hit to AAC73878.1 (136 aa), 84% identity in aa 1 - 136.
  
    0.543
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (24%) [HD]