Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ybiUPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73908.1); Blastp hit to AAC73908.1 (421 aa), 85% identity in aa 1 - 421. (421 aa)    
Predicted Functional Partners:
ybiV(1)
Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC73909.1); Blastp hit to AAC73909.1 (271 aa), 88% identity in aa 1 - 269.
  
  
 0.567
preT
Putative NADPH-dependent glutamate synthase beta chain or related oxidoreductase; Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity).
  
  
 0.531
aegA
Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC75521.1); Blastp hit to AAC75521.1 (659 aa), 85% identity in aa 1 - 651.
  
  
 0.531
fadH
2,4-dieonyl-coa reductase; Similar to E. coli putative NADPH dehydrogenase (AAC76116.1); Blastp hit to AAC76116.1 (672 aa), 85% identity in aa 1 - 672.
  
  
 0.531
gltD
Similar to E. coli glutamate synthase, small subunit (AAC76245.1); Blastp hit to AAC76245.1 (472 aa), 95% identity in aa 1 - 472.
  
  
 0.531
ybiV(2)
Putative hydrolase of the HAD superfamily; Similar to E. coli orf, hypothetical protein (AAC73909.1); Blastp hit to AAC73909.1 (271 aa), 94% identity in aa 33 - 269.
  
  
 0.510
cysI
NADPH dependent sulfite reductase, alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.474
sgaB
Putative PTS enzyme IIsga subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.
  
     0.442
malT
Transcriptional activator of the mal genes; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
  
     0.436
yfaW
Putative galactonate dehydratase; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate. Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
  
     0.414
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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