Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yliAPutative ATPase components of ABC-type transport system, contain duplicated ATPase domain; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family. (623 aa)    
Predicted Functional Partners:
yliC
Putative ABC transporter periplasmic binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane.
 0.999
yliD
Putative ABC transporter inner membrane component; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane.
 0.999
yliB
Putative ABC transporter periplasmic binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Binds glutathione.
 
 0.998
ybiK
Putative asparaginase; Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues). Degrades L-isoaspartyl-containing di- and tripeptides. Acts best on iso-Asp-Leu, followed by iso-Asp-Ala, -His and to a lesser extent iso-Asp-Lys, -Phe and iso-Asp-Leu-Ala. Does not act on internal iso-Asp bonds (Als-iso-Asp-Leu-Ala). Does not act on alpha-Asp bonds. Has poor L-asparaginase activity. Belongs to the Ntn-hydrolase family.
  
 0.991
oppC
Oligopeptide transport protein; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
 
 0.985
dppC
Dipeptide transport protein 2; ABC superfamily (membrane); similar to E. coli dipeptide transport system permease protein 2 (AAC76567.1); Blastp hit to AAC76567.1 (300 aa), 94% identity in aa 1 - 300.
 
 0.984
STM1257
Putative ABC transporter; Putative transmembrane protein (gi|2337944).
 
 0.947
sapC
ABC superfamily peptide transport protein; Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
     0.945
dppB
Dipeptide transport protein 1; ABC superfamily (membrane); similar to E. coli dipeptide transport system permease protein 1 (AAC76568.1); Blastp hit to AAC76568.1 (339 aa), 97% identity in aa 1 - 339.
 
 0.866
STM1256
Putative ABC transporter; Putative transmembrane protein (gi|2337943).
 
 
 0.856
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (44%) [HD]