STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM0867Putative hydrolase; Similar to E. coli orf, hypothetical protein (AAC73931.1); Blastp hit to AAC73931.1 (262 aa), 82% identity in aa 1 - 261. (271 aa)    
Predicted Functional Partners:
ribD
Pyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.921
ribF
Flavokinase and FAD synthetase; Similar to E. coli putative regulator (AAC73136.1); Blastp hit to AAC73136.1 (313 aa), 89% identity in aa 1 - 309; Belongs to the ribF family.
   
 0.909
ribH
Riboflavin synthase, beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity); Belongs to the DMRL synthase family.
     
 0.905
ribE
Similar to E. coli riboflavin synthase, alpha chain (AAC74734.1); Blastp hit to AAC74734.1 (213 aa), 90% identity in aa 1 - 208.
     
 0.901
yigB
Putative hydrolase of the HAD superfamily; Similar to E. coli putative phosphatase (AAC76815.1); Blastp hit to AAC76815.1 (238 aa), 87% identity in aa 1 - 238.
     
 0.901
hpaC
4-hydroxyphenylacetate catabolism protein; Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion (By similarity); Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
     
  0.900
ubiB
FMN reductase; Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides; Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
   
 
  0.900
aphA
Non-specific acid phosphatase/phosphotransferase, class B; Dephosphorylates several organic phosphate monoesters such as 3'-UMP, 5'-UMP and pNPP. Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds such as the 2'-, 3-, or 5'-hydroxyls of nucleosides and nucleotides. Also displays significant phosphomutase activity since it is able to catalyze the transfer of the phosphate group of 3'-AMP from the 3'-position both to the 2'- and 5'-positions. One of the physio [...]
     
  0.900
phoN
Nonspecific acid phosphatase precursor. (SW:PHON_SALTY).
     
  0.900
STM0868
Similar to E. coli putative DEOR-type transcriptional regulator (AAC73932.1); Blastp hit to AAC73932.1 (402 aa), 87% identity in aa 1 - 402.
  
    0.873
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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