STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ybjRSimilar to E. coli putative regulator (AAC73954.1); Blastp hit to AAC73954.1 (276 aa), 81% identity in aa 1 - 276. (276 aa)    
Predicted Functional Partners:
ybjQ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73953.1); Blastp hit to AAC73953.1 (107 aa), 94% identity in aa 1 - 107; Belongs to the UPF0145 family.
 
    0.983
yfeW
Similar to E. coli putative beta-lactamase (AAC75483.1); Blastp hit to AAC75483.1 (463 aa), 72% identity in aa 30 - 461; Belongs to the peptidase S12 family. YfeW subfamily.
 
    
 0.913
STM3036
Putative inner membrane protein.
     
 0.912
thiE
Thiamin phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
      0.878
ycgQ
Putative resistance protein MccF; Homologs of microcin C7; similar to E. coli orf, hypothetical protein (AAC74276.1); Blastp hit to AAC74276.1 (304 aa), 79% identity in aa 1 - 304.
  
  
 0.694
rstA
Similar to E. coli response transcriptional regulatory protein (RstB sensor) (AAC74680.1); Blastp hit to AAC74680.1 (242 aa), 84% identity in aa 4 - 242.
      
 0.677
nagZ
Putative glycosyl hydrolase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Plays a role in beta-lactam antibiotic resistance via its role in generating anhydro-N-acetylmuramic acid-linked peptides; these peptides function as signaling molecules that induce high-level expression of the beta-lactamase AmpC; Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
    
 0.630
yjbA
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77000.1); Blastp hit to AAC77000.1 (136 aa), 87% identity in aa 1 - 136; Belongs to the PsiE family.
   
  
 0.623
nupG
MFS family nucleoside transport; Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force; Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family.
  
     0.470
xapB
Similar to E. coli xanthosine permease (AAC75459.1); Blastp hit to AAC75459.1 (418 aa), 88% identity in aa 1 - 418.
  
     0.458
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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