| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA | acs | STM2337 | STM4275 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.986 |
| ackA | ldhA | STM2337 | STM1647 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | Similar to E. coli fermentative D-lactate dehydrogenase, NAD-dependent (AAC74462.1); Blastp hit to AAC74462.1 (329 aa), 94% identity in aa 1 - 328; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.615 |
| ackA | lldD | STM2337 | STM3694 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.485 |
| ackA | maeB | STM2337 | STM2472 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | Putative transferase; NADP-dependent malic enzyme. (SW:MAO2_SALTY); In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. | 0.758 |
| ackA | nifJ | STM2337 | STM1651 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.697 |
| ackA | pflB | STM2337 | STM0973 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | Pyruvate formate lyase I, induced anaerobically; Similar to E. coli formate acetyltransferase 1 (AAC73989.1); Blastp hit to AAC73989.1 (760 aa), 96% identity in aa 1 - 760. | 0.636 |
| ackA | poxB | STM2337 | STM0935 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | Pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors, cytoplasmic in absence of cofactors; Similar to E. coli pyruvate oxidase (AAC73958.1); Blastp hit to AAC73958.1 (572 aa), 94% identity in aa 1 - 572; Belongs to the TPP enzyme family. | 0.972 |
| ackA | pykF | STM2337 | STM1378 | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | Pyruvate kinase I; Formerly F; fructose stimulated; pyruvate kinase I. (SW:KPY1_SALTY). | 0.619 |
| acs | ackA | STM4275 | STM2337 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetate kinase A; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Has broad substrate specificity and can also utilize GTP, UTP and CTP. Can also phosphorylate propionate, but has very low activity with formate and is inactive with butyrate; Belongs to the acetokinase family. | 0.986 |
| acs | nifJ | STM4275 | STM1651 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.975 |
| acs | pflB | STM4275 | STM0973 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate formate lyase I, induced anaerobically; Similar to E. coli formate acetyltransferase 1 (AAC73989.1); Blastp hit to AAC73989.1 (760 aa), 96% identity in aa 1 - 760. | 0.920 |
| acs | poxB | STM4275 | STM0935 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors, cytoplasmic in absence of cofactors; Similar to E. coli pyruvate oxidase (AAC73958.1); Blastp hit to AAC73958.1 (572 aa), 94% identity in aa 1 - 572; Belongs to the TPP enzyme family. | 0.955 |
| ilvH | ilvN | STM0117 | STM3795 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Similar to E. coli acetolactate synthase I, valine sensitive, small subunit (AAC76693.1); Blastp hit to AAC76693.1 (96 aa), 90% identity in aa 1 - 96. | 0.960 |
| ilvH | ldhA | STM0117 | STM1647 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Similar to E. coli fermentative D-lactate dehydrogenase, NAD-dependent (AAC74462.1); Blastp hit to AAC74462.1 (329 aa), 94% identity in aa 1 - 328; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.808 |
| ilvH | lldD | STM0117 | STM3694 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. | 0.810 |
| ilvH | maeB | STM0117 | STM2472 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Putative transferase; NADP-dependent malic enzyme. (SW:MAO2_SALTY); In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. | 0.837 |
| ilvH | nifJ | STM0117 | STM1651 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.953 |
| ilvH | pflB | STM0117 | STM0973 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Pyruvate formate lyase I, induced anaerobically; Similar to E. coli formate acetyltransferase 1 (AAC73989.1); Blastp hit to AAC73989.1 (760 aa), 96% identity in aa 1 - 760. | 0.900 |
| ilvH | poxB | STM0117 | STM0935 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Pyruvate dehydrogenase/oxidase FAD and thiamine PPi cofactors, cytoplasmic in absence of cofactors; Similar to E. coli pyruvate oxidase (AAC73958.1); Blastp hit to AAC73958.1 (572 aa), 94% identity in aa 1 - 572; Belongs to the TPP enzyme family. | 0.962 |
| ilvH | pykF | STM0117 | STM1378 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Pyruvate kinase I; Formerly F; fructose stimulated; pyruvate kinase I. (SW:KPY1_SALTY). | 0.800 |
