STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ybjESimilar to E. coli putative surface protein (AAC73961.1); Blastp hit to AAC73961.1 (315 aa), 88% identity in aa 17 - 315. (299 aa)    
Predicted Functional Partners:
ylbE
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73621.1); Blastp hit to AAC73621.1 (333 aa), 94% identity in aa 1 - 332.
      
 0.762
ybjD
Homology with RecF protein; Similar to E. coli orf, hypothetical protein (AAC73963.1); Blastp hit to AAC73963.1 (552 aa), 89% identity in aa 1 - 552.
  
  
 0.588
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
      
 0.580
yjiY
Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721.
      
 0.577
wcaJ
Putative UDP-glucose lipid carrier transferase; In colanic acid gene cluster; similar to E. coli putative colanic acid biosynthsis UDP-glucose lipid carrier transferase (AAC75108.1); Blastp hit to AAC75108.1 (464 aa), 89% identity in aa 1 - 464; glucose-1-phosphate transferase.
      
 0.562
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.509
yccS
Putative efflux (PET) family transporter; Similar to E. coli orf, hypothetical protein (AAC74046.1); Blastp hit to AAC74046.1 (720 aa), 88% identity in aa 4 - 710.
  
    0.507
hcr
NADH oxidoreductase for hcp gene product; Similar to E. coli putative enzyme (AAC73959.1); Blastp hit to AAC73959.1 (322 aa), 90% identity in aa 1 - 322.
  
    0.497
yigM
Putative transport protein; Uptake of biotin; Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
  
     0.474
mukB
Kinesin-line cell division protein involved in sister chromosome partitioning; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
    0.464
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.