Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ybjXHomolog of virK; Similar to E. coli putative enzyme (AAC73964.1); Blastp hit to AAC73964.1 (330 aa), 57% identity in aa 15 - 329. (322 aa)    
Predicted Functional Partners:
mig-14
Putative transcription activator.
   
  
 0.632
yeeA
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75069.1); Blastp hit to AAC75069.1 (352 aa), 79% identity in aa 1 - 352.
  
     0.629
yihX
Similar to E. coli putative phosphatase (AAD13447.1); Blastp hit to AAD13447.1 (206 aa), 89% identity in aa 8 - 206.
      
 0.612
mgtA
P-type ATPase; Mediates magnesium influx to the cytosol.
      
 0.579
ybiP
Putative integral membrane protein; Similar to E. coli putative enzyme (AAC73902.1); Blastp hit to AAC73902.1 (527 aa), 84% identity in aa 1 - 526.
  
   
 0.570
ybjZ
Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
       0.563
ybjY
Similar to E. coli putative membrane protein (AAC73965.1); Blastp hit to AAC73965.1 (380 aa), 83% identity in aa 12 - 378; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
    0.555
yejM
Putative hydrolase of alkaline phosphatase superfamily; Hypothetical protein in rplY-proL intergenic region. (SW:YEJM_SALTY).
  
     0.539
nfnB
Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity).
  
    0.536
rfaJ
UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase; Adds the glucose(II) group on the galactose(I) group of LPS.
  
   
 0.528
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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