STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycaMPutative APC family, amino-acid transporter; Similar to E. coli putative transport (AAC73985.1); Blastp hit to AAC73985.1 (540 aa), 93% identity in aa 68 - 536. (473 aa)    
Predicted Functional Partners:
gapA
Glyceraldehyde-3-phosphate dehydrogenase A; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
      
 0.696
celC
Similar to E. coli PEP-dependent phosphotransferase enzyme III for cellobiose, arbutin, and salicin (AAC74806.1); Blastp hit to AAC74806.1 (116 aa), 87% identity in aa 1 - 115.
  
     0.564
celA
Similar to E. coli PEP-dependent phosphotransferase enzyme IV for cellobiose, arbutin, and salicin (AAC74808.1); Blastp hit to AAC74808.1 (106 aa), 96% identity in aa 1 - 106.
  
     0.547
STM0571
Putative inner membrane protein; Unknown (gi|2896134).
  
     0.541
STM4534
Putative NtrC family transcriptional regulator, ATPase domain protein; Similar to E. coli psp operon transcriptional activator (AAC74385.1); Blastp hit to AAC74385.1 (330 aa), 38% identity in aa 13 - 242.
  
     0.517
ycaD
Putative MFS family transport protein; Similar to E. coli putative transport (AAC73984.1); Blastp hit to AAC73984.1 (382 aa), 88% identity in aa 1 - 382.
  
    0.497
celB
PTS family sugar specific enzyme II for cellobiose, arbutin, and salicin; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
  
    0.438
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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