| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STM2377 | mdaA | STM2377 | STM0874 | Putative inner membrane protein. | Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. | 0.442 |
| STM2377 | nfnB | STM2377 | STM0578 | Putative inner membrane protein. | Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). | 0.442 |
| STM2377 | ycaO | STM2377 | STM0975 | Putative inner membrane protein. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | 0.794 |
| STM2377 | ydjA | STM2377 | STM1296 | Putative inner membrane protein. | Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74835.1); Blastp hit to AAC74835.1 (183 aa), 88% identity in aa 1 - 183. | 0.442 |
| STM2377 | yhiH | STM2377 | STM3586 | Putative inner membrane protein. | Putative ABC-type multidrug transport system; ATPase component; Permease component of an ABC-transporter; similar to E. coli putative ATP-binding component of a transport system, fragment 1 (AAC76511.1); Blastp hit to AAC76511.1 (894 aa), 89% identity in aa 1 - 894. | 0.682 |
| mdaA | STM2377 | STM0874 | STM2377 | Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. | Putative inner membrane protein. | 0.442 |
| mdaA | nfnB | STM0874 | STM0578 | Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. | Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). | 0.995 |
| mdaA | ycaO | STM0874 | STM0975 | Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | 0.624 |
| mdaA | yhiH | STM0874 | STM3586 | Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. | Putative ABC-type multidrug transport system; ATPase component; Permease component of an ABC-transporter; similar to E. coli putative ATP-binding component of a transport system, fragment 1 (AAC76511.1); Blastp hit to AAC76511.1 (894 aa), 89% identity in aa 1 - 894. | 0.625 |
| nfnB | STM2377 | STM0578 | STM2377 | Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). | Putative inner membrane protein. | 0.442 |
| nfnB | mdaA | STM0578 | STM0874 | Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). | Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. | 0.995 |
| nfnB | ycaO | STM0578 | STM0975 | Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | 0.615 |
| nfnB | yhiH | STM0578 | STM3586 | Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). | Putative ABC-type multidrug transport system; ATPase component; Permease component of an ABC-transporter; similar to E. coli putative ATP-binding component of a transport system, fragment 1 (AAC76511.1); Blastp hit to AAC76511.1 (894 aa), 89% identity in aa 1 - 894. | 0.625 |
| yabF | ycaO | STM0085 | STM0975 | Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | 0.660 |
| yabF | yedF | STM0085 | STM1966 | Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. | Putative transcriptional regulator; Hypothetical 8.6 Kda protein in amyA-fliE intergenic region (ORF 9). (SW:YEDF_ECOLI); Belongs to the sulfur carrier protein TusA family. | 0.472 |
| yabF | yohI | STM0085 | STM2174 | Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. | Putative nitrogen regulation protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.470 |
| ycaO | STM2377 | STM0975 | STM2377 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | Putative inner membrane protein. | 0.794 |
| ycaO | mdaA | STM0975 | STM0874 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | Oxygen-insensitive NADPH nitroreductase; Catalyzes the reduction of nitroaromatic compounds using NADPH. Has a broad electron acceptor specificity. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. | 0.624 |
| ycaO | nfnB | STM0975 | STM0578 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | Dihydropteridine reductase; Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity). | 0.615 |
| ycaO | yabF | STM0975 | STM0085 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73991.1); Blastp hit to AAC73991.1 (589 aa), 93% identity in aa 4 - 589. | Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. | 0.660 |
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