Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ycaRPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74003.1); Blastp hit to AAC74003.1 (60 aa), 93% identity in aa 1 - 60; Belongs to the UPF0434 family. (60 aa)    
Predicted Functional Partners:
kdsB
CTP:CMP-3-deoxy-D-manno-octulosonate transferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
  
 0.904
ygfZ
Putative aminomethyltransferase; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.
      
 0.853
phoL
Putative phosphate starvation-inducible protein, ATP-binding; Similar to E. coli putative ATP-binding protein in pho regulon (AAC73761.1); Blastp hit to AAC73761.1 (359 aa), 96% identity in aa 1 - 359.
   
  
 0.816
yhaL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76142.1); Blastp hit to AAC76142.1 (56 aa), 70% identity in aa 3 - 56.
      
 0.815
ybeD
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73732.1); Blastp hit to AAC73732.1 (87 aa), 97% identity in aa 1 - 87; Belongs to the UPF0250 family.
   
  
 0.766
lpxK
Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
     0.730
ycaI
Putative recombination protein; Similar to E. coli orf, hypothetical protein (AAC73999.1); Blastp hit to AAC73999.1 (780 aa), 70% identity in aa 27 - 780.
 
     0.718
ybbA
Putative ABC superfamily (atp_bind) transporter; Similar to E. coli putative ATP-binding component of a transport system (AAC73597.1); Blastp hit to AAC73597.1 (228 aa), 92% identity in aa 1 - 228.
      
 0.711
ydhL
Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC74720.1); Blastp hit to AAC74720.1 (125 aa), 83% identity in aa 47 - 125.
  
   
 0.689
ybbO
Similar to E. coli putative oxidoreductase (AAC73595.1); Blastp hit to AAC73595.1 (269 aa), 90% identity in aa 14 - 268.
   
  
 0.675
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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