Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ycbYPutative N6-adenine-specific DNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (702 aa)    
Predicted Functional Partners:
uup
Contains duplicated ATPase domain; similar to E. coli putative ATP-binding component of a transport system (AAC74035.1); Blastp hit to AAC74035.1 (635 aa), 94% identity in aa 1 - 634.
 
  
 0.982
ygdD
Putative small membrane protein; Similar to E. coli orf, hypothetical protein (AAC75849.1); Blastp hit to AAC75849.1 (131 aa), 90% identity in aa 1 - 131.
 
   
 0.802
pqiA
Similar to E. coli paraquat-inducible protein A (AAC74036.1); Blastp hit to AAC74036.1 (417 aa), 89% identity in aa 1 - 417.
  
    0.794
pqiB
Similar to E. coli paraquat-inducible protein B (AAC74037.1); Blastp hit to AAC74037.1 (546 aa), 89% identity in aa 1 - 546.
  
    0.787
ymbA
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74038.1); Blastp hit to AAC74038.1 (182 aa), 83% identity in aa 1 - 182.
  
    0.786
rsuA
16S rRNA pseudouridylate 516 synthase; Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
 
 
 0.777
ygjO
Putative methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
   
  
 0.770
ygiR
Putative Fe-S oxidoreductase family 2; Similar to E. coli orf, hypothetical protein (AAC76051.1); Blastp hit to AAC76051.1 (413 aa), 46% identity in aa 1 - 26.
  
  
 0.766
ybiN
Putative SAM-dependent methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA.
   
  
 0.757
ybjF
Putative tRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
  
  
 0.755
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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