Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uupContains duplicated ATPase domain; similar to E. coli putative ATP-binding component of a transport system (AAC74035.1); Blastp hit to AAC74035.1 (635 aa), 94% identity in aa 1 - 634. (635 aa)    
Predicted Functional Partners:
ycbY
Putative N6-adenine-specific DNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
 
  
 0.982
pqiA
Similar to E. coli paraquat-inducible protein A (AAC74036.1); Blastp hit to AAC74036.1 (417 aa), 89% identity in aa 1 - 417.
  
    0.779
ymbA
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC74038.1); Blastp hit to AAC74038.1 (182 aa), 83% identity in aa 1 - 182.
  
    0.777
pqiB
Similar to E. coli paraquat-inducible protein B (AAC74037.1); Blastp hit to AAC74037.1 (546 aa), 89% identity in aa 1 - 546.
  
    0.775
rplY
50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.
  
   0.715
rplX
50S ribosomal subunit protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
   
 
 0.710
rpmC
Similar to E. coli 50S ribosomal subunit protein L29 (AAC76337.1); Blastp hit to AAC76337.1 (63 aa), 98% identity in aa 1 - 63; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.698
rplF
50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
 
 0.691
rplT
50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).
   
 
 0.686
rplU
50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.681
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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