| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobB | yccR | STM1221 | STM1072 | Putative nicotinate-nucleotide dimethylbenzimidazolephosphoribosltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form (By similarity). Activates the enzyme acetyl-CoA synthetase by deacetylating 'Lys-609' in the inactive, acetylated form of the enzyme. May also modulate the activity of other propionyl-adenosine monophosphate (AMP)-forming enzymes. Overexpression compensates for a cobT deletion, suggesting it may have [...] | Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. | 0.747 |
| hnr | nlpB | STM1753 | STM2488 | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.705 |
| hnr | yccR | STM1753 | STM1072 | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. | 0.707 |
| hnr | ychA | STM1753 | STM1773 | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | Putative transcriptional regulator; Required for maximal expression of sirC, not required to invade host cells; Belongs to the UPF0162 family. | 0.566 |
| hnr | ycjI | STM1753 | STM1680 | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | Similar to E. coli putative carboxypeptidase (AAC74408.1); Blastp hit to AAC74408.1 (262 aa), 90% identity in aa 21 - 262. | 0.556 |
| hnr | ydbH | STM1753 | STM1646 | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74463.1); Blastp hit to AAC74463.1 (879 aa), 78% identity in aa 1 - 878. | 0.638 |
| hnr | yeiU | STM1753 | STM2213 | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | Putative permease; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. | 0.667 |
| hnr | ygfB | STM1753 | STM3059 | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75947.1); Blastp hit to AAC75947.1 (194 aa), 93% identity in aa 1 - 194; Belongs to the UPF0149 family. | 0.681 |
| nlpB | hnr | STM2488 | STM1753 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.705 |
| nlpB | yccR | STM2488 | STM1072 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. | 0.758 |
| nlpB | ycdY | STM2488 | STM1137 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Similar to E. coli putative oxidoreductase component (AAC74119.1); Blastp hit to AAC74119.1 (184 aa), 86% identity in aa 1 - 184. | 0.573 |
| nlpB | ychA | STM2488 | STM1773 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative transcriptional regulator; Required for maximal expression of sirC, not required to invade host cells; Belongs to the UPF0162 family. | 0.701 |
| nlpB | ycjI | STM2488 | STM1680 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Similar to E. coli putative carboxypeptidase (AAC74408.1); Blastp hit to AAC74408.1 (262 aa), 90% identity in aa 21 - 262. | 0.539 |
| nlpB | ydbH | STM2488 | STM1646 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74463.1); Blastp hit to AAC74463.1 (879 aa), 78% identity in aa 1 - 878. | 0.656 |
| nlpB | yeiU | STM2488 | STM2213 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative permease; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. | 0.574 |
| nlpB | ygfB | STM2488 | STM3059 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75947.1); Blastp hit to AAC75947.1 (194 aa), 93% identity in aa 1 - 194; Belongs to the UPF0149 family. | 0.711 |
| ybiO | yccR | STM0827 | STM1072 | Similar to E. coli putative transport protein (AAC73895.1); Blastp hit to AAC73895.1 (786 aa), 85% identity in aa 46 - 786. | Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. | 0.857 |
| yccR | cobB | STM1072 | STM1221 | Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. | Putative nicotinate-nucleotide dimethylbenzimidazolephosphoribosltransferase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form (By similarity). Activates the enzyme acetyl-CoA synthetase by deacetylating 'Lys-609' in the inactive, acetylated form of the enzyme. May also modulate the activity of other propionyl-adenosine monophosphate (AMP)-forming enzymes. Overexpression compensates for a cobT deletion, suggesting it may have [...] | 0.747 |
| yccR | hnr | STM1072 | STM1753 | Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. | Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.707 |
| yccR | nlpB | STM1072 | STM2488 | Putative DNA transformation protein; Similar to E. coli orf, hypothetical protein (AAC74045.1); Blastp hit to AAC74045.1 (209 aa), 75% identity in aa 1 - 199. | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.758 |
