STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM1082Similar to E. coli putative ARAC-type regulatory protein (AAC73647.1); Blastp hit to AAC73647.1 (265 aa), 33% identity in aa 8 - 260. (259 aa)    
Predicted Functional Partners:
STM0909
Fels-1 prophage protein.
      
 0.897
STM1081
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC73646.1); Blastp hit to AAC73646.1 (183 aa), 59% identity in aa 1 - 180.
 
    0.874
pduO
Propanediol utilization B12 related protein; Belongs to the Cob(I)alamin adenosyltransferase family.
   
  
 0.726
STM2703
Fels-2 prophage protein; Similar to invertase (pin) in phage E14; unknown (gi|2852344).
      
 0.724
invE
Invasion protein; Involved in the triggering of intracellular events that lead to microbial internalization. These events include increase in calcium level, redistribution of actin microfilaments, and changes in the normal structure of the microvilli. Encoded within the type III secretion system (SPI-1 TTSS), it is essential for the translocation of protein effectors into host cells. Forms a complex with SipB and SipC in the presence of their chaperone SicA. Positively regulates the secretion of SPI-1 TTSS effector proteins SipB, SipC and SipD and negatively influences the secretion of [...]
      
 0.679
yccX
Putative phosphohydrolase; Similar to E. coli orf, hypothetical protein (AAC74054.1); Blastp hit to AAC74054.1 (92 aa), 78% identity in aa 1 - 92.
  
    0.662
gogB
Gifsy-1 prophage leucine-rich repeat protein.
      
 0.646
ybhB
Putative phospholipid-binding protein; Similar to E. coli orf, hypothetical protein (AAC73860.1); Blastp hit to AAC73860.1 (158 aa), 93% identity in aa 1 - 158.
 
    0.500
STM3198
Putative inner membrane protein; Similar to E. coli putative oxidoreductase (AAC76086.1); Blastp hit to AAC76086.1 (209 aa), 72% identity in aa 1 - 201.
  
     0.494
araC
Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.
  
   
 0.467
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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