STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaG4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative isomerase (AAC74264.1); Blastp hit to AAC74264.1 (219 aa), 38% identity in aa 22 - 219, 29% identity in aa 35 - 211. (429 aa)    
Predicted Functional Partners:
hpaF
4-hydroxyphenylacetate catabolism protein.
 
 
 0.998
hpaH
4-hydroxyphenylacetate catabolism protein; Similar to E. coli 2-keto-4-pentenoate hydratase (AAC73453.1); Blastp hit to AAC73453.1 (271 aa), 34% identity in aa 6 - 261.
 
 
 0.996
hpaD
4-hydroxyphenylacetate catabolism protein.
 
  
 0.990
hpaI
4-hydroxyphenylacetate catabolism protein; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
  
  
 0.939
hpaE
4-hydroxyphenylacetate catabolism protein; Similar to E. coli aldehyde dehydrogenase, prefers NADP over NAD (AAC74382.1); Blastp hit to AAC74382.1 (495 aa), 39% identity in aa 23 - 493.
 
 
 0.901
hpaR
4-hydroxyphenylacetate catabolism protein.
 
  
 0.877
STM2617
Gifsy-1 prophage protein; Similar to antiterminator Q.
      
 0.764
ydfZ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74614.1); Blastp hit to AAC74614.1 (67 aa), 79% identity in aa 1 - 67.
      
 0.716
hpaA
4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 25% identity in aa 181 - 281.
 
    0.628
STM2177
Putative flutathione S-transferase; Similar to E. coli putative isomerase (AAC74264.1); Blastp hit to AAC74264.1 (219 aa), 38% identity in aa 14 - 211.
  
 
 
0.614
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (38%) [HD]