STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaI4-hydroxyphenylacetate catabolism protein; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde. (263 aa)    
Predicted Functional Partners:
hpaH
4-hydroxyphenylacetate catabolism protein; Similar to E. coli 2-keto-4-pentenoate hydratase (AAC73453.1); Blastp hit to AAC73453.1 (271 aa), 34% identity in aa 6 - 261.
 
 0.999
hpaF
4-hydroxyphenylacetate catabolism protein.
 
  
 0.992
hpaD
4-hydroxyphenylacetate catabolism protein.
 
  
 0.990
yfaV
Similar to E. coli putative transport protein (AAC75306.1); Blastp hit to AAC75306.1 (442 aa), 91% identity in aa 14 - 442.
 
  
 0.961
hpaG
4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative isomerase (AAC74264.1); Blastp hit to AAC74264.1 (219 aa), 38% identity in aa 22 - 219, 29% identity in aa 35 - 211.
  
  
 0.939
gabD
Similar to E. coli succinate-semialdehyde dehydrogenase, NADP-dependent activity (AAC75708.1); Blastp hit to AAC75708.1 (482 aa), 90% identity in aa 1 - 482.
  
 
  0.911
STM4519
Similar to E. coli putative aldehyde dehydrogenase (AAC74598.1); Blastp hit to AAC74598.1 (470 aa), 42% identity in aa 19 - 465.
  
 
  0.903
yfaX
Similar to E. coli putative regulator (AAC75308.1); Blastp hit to AAC75308.1 (260 aa), 87% identity in aa 1 - 260.
      
 0.897
yfaW
Putative galactonate dehydratase; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR). Can also dehydrate L-lyxonate and L-mannonate, although less efficiently, but not 2-keto-4-hydroxyheptane-1,7-dioate. Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
  
  
 0.846
hpaA
4-hydroxyphenylacetate catabolism protein; Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 25% identity in aa 181 - 281.
 
    0.806
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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